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Российский биотерапевтический журнал

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ДОФАМИНЕРГИЧЕСКАЯ СИСТЕМА: СТРЕСС, ДЕПРЕССИЯ, РАК (ЧАСТЬ 2)

https://doi.org/10.17650/1726-9784-2019-18-4-25-33

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Аннотация

Во многих ситуациях в современном мире мы подвержены стрессу. Вместе с тем, если острый стресс может иметь положительное воздействие на организм, постоянное стрессирование, как правило, наносит вред здоровью, приводя к серьезным заболеваниям, в том числе к раку, который считают болезнью старения. Выявлено, что стресс может ускорять опухолевый рост, ослаблять противоопухолевый иммунитет и эффективность химиотерапии. Из данных литературы известно, что дофамин, недостаток которого играет существенную роль при старении и стрессе, ограничивает развитие опухолей. Роль центральных нейрональных процессов с участием дофаминергической системы в механизмах контроля злокачественного роста обсуждается в представленном обзоре.

Об авторах

О. А. Бочарова
ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Блохина» Минздрава России
Россия
Россия, 115478 Москва, Каширское шоссе, 24


Е. В. Бочаров
ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Блохина» Минздрава России
Россия
Россия, 115478 Москва, Каширское шоссе, 24


В. Г. Кучеряну
ФГБНУ «Научно-исследовательский институт общей патологии и патофизиологии»
Россия

Россия, 125315 Москва, ул. Балтийская, 8



Р. В. Карпова
ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Блохина» Минздрава России
Россия
Россия, 115478 Москва, Каширское шоссе, 24


А. А. Вершинская
ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Блохина» Минздрава России
Россия

Россия, 115478 Москва, Каширское шоссе, 24



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Для цитирования:


Бочарова О.А., Бочаров Е.В., Кучеряну В.Г., Карпова Р.В., Вершинская А.А. ДОФАМИНЕРГИЧЕСКАЯ СИСТЕМА: СТРЕСС, ДЕПРЕССИЯ, РАК (ЧАСТЬ 2). Российский биотерапевтический журнал. 2019;18(4):25-33. https://doi.org/10.17650/1726-9784-2019-18-4-25-33

For citation:


Bocharova O.A., Bocharov E.V., Kucheryanu V.G., Karpova R.V., Vershinskaya A.A. DOPAMINERGIC SYSTEM: STRESS, DEPRESSION AND CANCER (PART 2). Russian Journal of Biotherapy. 2019;18(4):25-33. (In Russ.) https://doi.org/10.17650/1726-9784-2019-18-4-25-33

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