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Russian Journal of Biotherapy

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EVALUATING THE EFFECTIVENESS OF THE COMBINED TREATMENT OF PATIENTS WITH COLORECTAL CANCER, BREAST CANCERAND CANCER OF THE FLOOR OF THE MOUTH USING A STERILE HYDROGEL MATERIAL "KOLEGEL 5-FTUR"

https://doi.org/10.17650/1726-9784-2015-14-4-99-103

Abstract

The article is devoted to the effectiveness evaluation of the use of sterile material «Kolegel 5-ftur» on the basis of sodium alginate with 5-fluorouracil, as of shape of disk, in the course of chemoradiotherapy in patients with rectal cancer, breast cancer and cancer of the floor of the mouth. The study group included 38 patients: 19 patients diagnosed with CRR, 10 patients -BC, 9 patients - a cancer of the mouth floor. The study used a hydrogel material «Kolegel 5-ftur» during chemoradia- tion therapy for histologically confirmed diagnosis of a malignant tumor. The effectiveness of the combined treatment is proved by the following criteria: local control of the tumor, the analysis of toxicity and immediate effect. Thus, the use of hydrogel materials «Kolegel-5-ftur» in group of patients with primary malignant tumor localization in the floor of the mouth, with the aggressive chemotherapy provided enhancing the effectiveness of therapy.

About the Authors

L. I. Korytova
FSBI "Russian Scientific Center of Radiology and Surgical Technologies"
Russian Federation


V. P. Sokurenko
FSBI "Russian Scientific Center of Radiology and Surgical Technologies"
Russian Federation


E. A. Maslyukova
FSBI "Russian Scientific Center of Radiology and Surgical Technologies"
Russian Federation


A. V. Meshechkin
FSBI "Russian Scientific Center of Radiology and Surgical Technologies"
Russian Federation


N. D. Oltarzhevskaya
LLC «COLETEX»
Russian Federation


M. A. Korovina
LLC «COLETEX»
Russian Federation


I. V. Gusev
LLC «COLETEX»
Russian Federation


A. D. Kuznetsov
FSBI "Russian Scientific Center of Radiology and Surgical Technologies"
Russian Federation


V. G. Krasnikova
FSBI "Russian Scientific Center of Radiology and Surgical Technologies"
Russian Federation


E. M. Obuhov
FSBI "Russian Scientific Center of Radiology and Surgical Technologies"
Russian Federation


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Review

For citations:


Korytova L.I., Sokurenko V.P., Maslyukova E.A., Meshechkin A.V., Oltarzhevskaya N.D., Korovina M.A., Gusev I.V., Kuznetsov A.D., Krasnikova V.G., Obuhov E.M. EVALUATING THE EFFECTIVENESS OF THE COMBINED TREATMENT OF PATIENTS WITH COLORECTAL CANCER, BREAST CANCERAND CANCER OF THE FLOOR OF THE MOUTH USING A STERILE HYDROGEL MATERIAL "KOLEGEL 5-FTUR". Russian Journal of Biotherapy. 2015;14(4):99-103. (In Russ.) https://doi.org/10.17650/1726-9784-2015-14-4-99-103

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ISSN 1726-9784 (Print)
ISSN 1726-9792 (Online)