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Russian Journal of Biotherapy

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ORIGINAL REPORTS

 
Issue Title
 
Vol 24, No 3 (2025) Neutralizing ability of monoclonal antibodies directed to epitopes of functionally significant Streptococcus pneumoniae pneumolysin domain Abstract   PDF (Rus)
Ekaterina A. Kurbatova, Irina V. Yakovleva, Natalya F. Gavrilova, Denis S. Vorobyev, Ekaterina E. Petukhova, Irina B. Semenova, Anton E. Zaitsev, Yuri V. Volokh, Nune O. Vartanova, Alexander V. Poddubikov, Olga M. Afanasyeva, Alexander A. Zubkov
 
Vol 24, No 3 (2025) Modification of the red fluorescent protein TagRFP to reduce its immunogenicity in establishing fluorescent model tumors in immunocompetent Balb / C mice Abstract   PDF (Rus)
Nadezhda K. Marynich, Alexandra V. Gavshina, Irina G. Meerovich
 
Vol 24, No 3 (2025) Optimization of wet granulation by surface response method in obtaining GSB-106 tablets Abstract   PDF (Rus)
Sergey V. Tishkov, Evgenia V. Blynskaya, Konstantin V. Alekseev, Vladimir L. Dorofeev
 
Vol 24, No 3 (2025) Anemic syndrome in patients with rectal cancer Abstract   PDF (Rus)
Valentina N. Blindar, Igor A. Klimanov
 
Vol 24, No 3 (2025) Prognostic significance of TWIST and E-cadherin expression in primary tumor blocks of patients with early-stage melanoma and locally advanced rectal cancer: impact on disease outcome and therapy effectiveness Abstract   PDF (Rus)
Elizaveta A. Pasechnikova, Anastasiia Yu. Georgieva, Vadim N. Bodnya, Dmitry V. Kadomtsev, Vladimir A. Porkhanov, Alexandr A. Verevkin, Sofia D. Maksimenko
 
Vol 24, No 3 (2025) Detection of minimal residual disease after induction chemotherapy and autologous HSCT and its clinical significance in multiple myeloma Abstract   PDF (Rus)
Svetlana V. Chulkova, Natalia A. Kupriyshina, Anastasiya A. Semenova, Olga P. Kolbatskaya, Gayane S. Tumyan
 
Vol 24, No 3 (2025) Glucose-dependent adenosine triphosphate synthesis and GLUT transporter expression in RPMI8226 myeloma cells Abstract   PDF (Rus)
Sain S. Shushanov, Artur R. Gizatullin, Yulia B. Chernykh, Tatiana A. Zakharova, Natalia P. Akentieva
 
Vol 24, No 3 (2025) Production and characterization of monoclonal antibodies to synthetic human ferroportin peptide Abstract   PDF (Rus)
Margarita G. Khotuleva, Yana O. Sadovskaya, Anastasia O. Karimova, Nikolay E. Varlamov, Dmitriy A. Khochenkov, Maria V. Mironova, Dmitriy V. Gusev, Olga N. Solopova
 
Vol 24, No 3 (2025) A new indolo[2,3-a]carbazole N-glycoside derivative LCS-1269 with antitumor activity on transplantable mice tumors Abstract   PDF (Rus)
Marina P. Kiseleva, Irina S. Golubeva, Larisa M. Borisova, Galina B. Smirnova, Julia A. Borisova, Anna V. Lantsova, Dmitriy V. Gusev, Zoya S. Shprakh
 
Vol 24, No 2 (2025) Physical-chemical and thermal studies of solid dispersions of desloratadine Abstract   PDF (Rus)
Yu. A. Polkovnikova, D. D. Beginina, U. A. Tulskaya, A. S. Lenshin, A. A. Golovina
 
Vol 24, No 2 (2025) Development and validation of bioanalytical technique for the LCS-1269 assay by high-performance liquid chromatography Abstract   PDF (Rus)
D. A. Kozin, N. Yu. Kulbachevskaya, V. A. Balykov, Z. S. Shprakh
 
Vol 24, No 2 (2025) Development of the composition and characteristics of a wound-healing gel with L-arginine Abstract   PDF (Rus)
V. Yu. Rytchenkova, S. V. Rytchenkov, E. F. Stepanova, D. S. Yudin, S. V. Poroyskiy
 
Vol 24, No 2 (2025) Preclinical characteristics of siRNA duplexes as targeted adjuvants in malignant growth Abstract   PDF (Rus)
H. N. Treshalina, G. B. Smirnova, A. Yu. Kuzevanova, S. Sh. Karshieva, M. V. Kiselevskiy, A. V. Karpukhin, M. A. Maslov, A. A. Alimov
 
Vol 24, No 2 (2025) Evaluation of neurotoxicity of anthrafuran, a new antitumor drug from the anthracenediones class Abstract   PDF (Rus)
V. A. Polozkova, M. I. Treshchalin, S. G. Yazeryan, A. E. Shchekotikhin, E. R. Pereverzeva
 
Vol 24, No 2 (2025) Evaluation of the effects of different interleukin combinations on proliferation and cytotoxicity of natural killer cells Abstract   PDF (Rus)
P. O. Fedorova, I. O. Chikileva
 
Vol 24, No 2 (2025) Phytocomponents screening for oncoprotector development Abstract   PDF (Rus)
O. A. Bocharova, A. A. Aksyonov, R. V. Karpova, E. V. Bocharov, N. N. Kasatkina, I. V. Kazeev, M. V. Utkina, V. G. Kucheryanu, V. S. Kosorukov, I. S. Stilidi
 
Vol 24, No 1 (2025) Biological aspects of the polylactide-based composite materials application in orthopedics Abstract   PDF (Rus)
P. M. Kachalina, P. A. Kovaleva, A. I. Cheremnykh, V. A. Lvov, N. Yu. Anisimova
 
Vol 24, No 1 (2025) Osteoconductivity and biocompatibility of beta-titanium alloy Ti-15Mo with biomimetic coating in vitro Abstract   PDF (Rus)
S. A. Gatina, A. A. Gaysina, V. V. Polyakova, V. R. Aubakirova, N. Yu. Anisimova, N. А. Enikeev
 
Vol 24, No 1 (2025) Correlation of CD71 transferrin receptor expression with ICAM-1 adhesion molecule expression by breast cancer cells Abstract   PDF (Rus)
S. V. Chulkova, E. N. Sholokhova, I. V. Poddubnaya, I. S. Stylidi
 
Vol 24, No 1 (2025) The use of three-factor dispersion analysis to develop the composition of solutions for pharmaceutical printing of films dispersed in the oral cavity based on the substance 2-ethyl-6-methyl-3-hydroxypyridine succinate Abstract   PDF (Rus)
S. V. Tishkov, V. K. Alekseev, E. V. Blynskaya, S. N. Suslina
 
Vol 23, No 4 (2024) FCGR3A (CD16A) and FCGR3B (CD16B) mRNA levels in the blood of prostate cancer patients Abstract   PDF (Rus)
D. V. Novikov, Kh. M. Arioua, O. A. Korovin, A. V. Kalugin, S. V. Shumilova, A. V. Alyasova, L. Hamidani, V. V. Novikov
 
Vol 23, No 4 (2024) Comparative pharmacokinetics of pembrolizumab after single intravenous administration to Macaca fascicularis Abstract   PDF (Rus)
V. M. Kosman, M. V. Karlina, T. N. Barybina, N. M. Faustova, A. A. Matichin, V. G. Makarov, M. N. Makarova, A. A. Dmitrieva, E. V. Shipaeva, A. I. Podolyakina, O. V. Filon, M. Yu. Samsonov, V. G. Ignatiev
 
Vol 23, No 4 (2024) Changes in the STR profile of cells in the process of obtaining a stable cell line Abstract   PDF (Rus)
A. A. Malchenkova, E. N. Kosobokova
 
Vol 23, No 4 (2024) Features of albino rats and Wistar rats as biomodels for preclinical research Abstract   PDF (Rus)
M. I. Treshchalin, V. A. Polozkova, S. G. Yazeryan, E. R. Pereverzeva
 
Vol 23, No 3 (2024) Study and selection of optimal rheological characteristics of piracetam gel compositions for intranasal use Abstract   PDF (Rus)
E. F. Stepanova, E. V. Kovtun, N. D. Bunyatyan, Moneb M. Y. Dadou, I. M. Privalov, A. P. Pleten
 
Vol 23, No 3 (2024) Analysis of changes in the levels of soluble molecules CD50, CD54 and CD95 in the blood serum of patients with uterine fibroids depending on the characteristics of the disease (pilot study) Abstract   PDF (Rus)
A. V. Alyasova, M. E. Mamaeva, N. I. Kubysheva, V. V. Novikov
 
Vol 23, No 3 (2024) Effect of human reovirus strain R-92 on tumor cell lines Abstract   PDF (Rus)
S. Yu. Filippova, A. O. Sitkovskaya, I. V. Mezhevova, E. Yu. Zlatnik, I. A. Novikova, L. Yu. Vladimirova, Yu. V. Przhedetskiy, E. A. Dzhenkova, S. A. Kolpakov, E. P. Kolpakova, E. Yu. Kirichenko, A. K. Logvinov
 
Vol 23, No 3 (2024) Development of a model of a dosage form for a new domestic compound (pyrrolo[3,2-l]acridinone derivative) and studying its cytotoxic activity Abstract   PDF (Rus)
A. V. Lantsova, E. V. Sanarova, L. L. Nikolaeva, D. A. Lantsova, Yu. V. Shklyaev, A. E. Barmashov, N. L. Solovieva, M. A. Baryshnikova
 
Vol 23, No 3 (2024) Iron oxide nanoparticles as potential agents for combined radiotherapy Abstract   PDF (Rus)
M. V. Shestovskaya, A. L. Luss, V. V. Makarov, V. S. Yudin, A. A. Keskinov
 
Vol 23, No 3 (2024) Artificial intelligence tools for molecular analysis of sensitization profiles in patients with atopic dermatitis and bronchial asthma Abstract   PDF (Rus)
D. S. Fomina, M. S. Lebedkina, E. A. Nikitina, A. D. Dushkin, A. A. Chernov, Yu. D. Yukhnovskaya, I. V. Evsegneeva, A. V. Karaulov, M. A. Lysenko
 
Vol 23, No 2 (2024) The two types of immune microenvironment of renal cancer Abstract   PDF (Rus)
A. A. Borunova, A. A. Alimov, I. B. Shoua, A. I. Chertkova, Z. G. Kadagidze, A. Yu. Kuzevanova, N. K. Zhumabaev, F. M. Abdul, O. A. Khalmurzaev, K. S. Nemtseva, А. V. Matveev, P. V. Kononets, V. B. Matveev, T. N. Zabotina
 
Vol 23, No 2 (2024) Study of the risks of radiation induced reactions in patients receiving irradiation of the pelvic organs Abstract   PDF (Rus)
O. V. Korytov, L. I. Korytova, S. G. Grigorjev
 
Vol 23, No 2 (2024) Study of Ridostin Pro and Poly(I:C) as adjuvants for cancer vaccine on the E.G7-OVA model Abstract   PDF (Rus)
P. V. Tsarapaev, M. A. Baryshnikova, A. V. Ponomarev, A. A. Rudakova, Z. A. Sokolova, K. A. Baryshnikov, G. M. Levagina, E. D. Danilenko, V. S. Kosorukov
 
Vol 23, No 2 (2024) Development of technology and study of combination tablets of prednisolone and loratadine with modified release Abstract   PDF (Rus)
V. V. Davydova, E. F. Stepanova, A. M. Shevchenko, A. S. Chiriapkin, A. S. Pleten, A. A. Prokopov
 
Vol 23, No 1 (2024) Inhibitory effect of lomustine on the growth of spontaneous HER2-positive mammary tumors in transgenic mice Abstract   PDF (Rus)
V. A. Alexandrov, A. N. Stukov, Yu. G. Zmitrichenko, O. A. Belyaeva, G. V. Tochilnikov
 
Vol 23, No 1 (2024) Cytopathogenic effect of Streptococcus pneumoniae native pneumolysin in CHO-K1 cells Abstract   PDF (Rus)
E. A. Kurbatova, I. V. Yakovleva, N. F. Gavrilova, E. S. Petukhova, I. B. Semenova, A. E. Zaitsev, Yu. V. Volokh, A. Yu. Leonova, A. V. Poddubikov
 
Vol 23, No 1 (2024) Effect of solid dispersions with polyvinylpyrrolidone on the solubility of GML-3 Abstract   PDF (Rus)
V. B. Markeev, S. V. Tishkov, E. V. Blynskaya, K. V. Alekseev
 
Vol 23, No 1 (2024) Test Dissolution for quality control of water-insoluble somatostatine analog Abstract   PDF (Rus)
E. V. Ignatieva, M. N. Kraeva, I. V. Yartseva, D. V. Podymova, O. L. Orlova, D. V. Gusev, Ya. A. Poskedova, T. M. Litvinova, Z. S. Sprakh
 
Vol 23, No 1 (2024) Detection of circulating tumor DNA of B16-F10 melanoma syngenic model in C57BL6 mice plasma Abstract   PDF (Rus)
K. M. Konoplina, A. A. Malchenkova, N. A. Kalinina, M. V. Panyugina, E. N. Kosobokova, V. S. Kosorukov
 
Vol 23, No 1 (2024) B16 melanoma growth characteristic in C57BL/6 mice with various methods of obtaining tumor material and syngeneic tumor transplantation sites Abstract   PDF (Rus)
Ia. G. Murazov, Ia. V. Agatsarskaya, K. L. Kryshen
 
Vol 23, No 1 (2024) Effect of inactivating heterozygous mutations in DNA repair genes on experimental lung carcinogenesis in mice Abstract   PDF (Rus)
M. A. Maydin, M. N. Yurova, E. I. Fedoros, P. V. Sergiev, S. N. Aleksakhina, E. A. Otradnova, S. S. Kruglov, E. N. Imyanitov
 
Vol 22, No 4 (2023) Development of the test system based on enzyme immunoassay for the detection of recombinant Streptococcus pneumoniae pneumolysin Abstract   PDF (Rus)
E. A. Kurbatova, I. V. Yakovleva, N. F. Gavrilova, D. S. Vorobyev, E. S. Petukhova, I. B. Semenova, A. E. Zaitsev, Yu. V. Volokh, A. Yu. Leonova, A. V. Poddubikov, A. A. Kaloshin, I. M. Gruber
 
Vol 22, No 4 (2023) Solubilization of 3-hydroxyquinazoline derivative with antitumor activity Abstract   PDF (Rus)
E. V. Sanarova, A. V. Lantsova, L. L. Nikolaeva, V. N. Osipov, D. V. Gusev, L. M. Borisova
 
Vol 22, No 4 (2023) Modeling the release of vinpocetine from microcapsules based on sodium alginate and chitosan by molecular dynamics Abstract   PDF (Rus)
Yu. A. Polkovnikova
 
Vol 22, No 4 (2023) Analysis of the IL-10 mRNA level in the peripheral blood of patients with cancer and benign prostatic hyperplasia Abstract   PDF (Rus)
O. A. Korovin, A. V. Alyasova, Kh. M. Arioua, D. V. Novikov, N. V. Krasnogorova, V. V. Novikov
 
Vol 22, No 4 (2023) Innate immunity cells in a model of acute psoriasis-like inflammation in mice Abstract   PDF (Rus)
E. A. Akhmatova, E. V. Sorokina, I. Zh. IShubina, E. A. Kurbatova, V. N. Stolpnikova, E. O. Kalinichenko, I. V. Bisheva, S. A. Skhodova
 
Vol 22, No 3 (2023) Changes in urine metabolite concentration as a minimally invasive marker of ovarian serous adenocarcinoma Abstract   PDF (Rus)
O. N. Guskova, I. A. Alliluev, E. V. Verenikina, V. V. Polovodova, M. A. Rogozin, T. Yu. Myagkova, M. L. Adamyan, O. E. Zhenilo, N. M. Abdullaeva, M. R. Tsandekova, N. D. Ushakova, D. S. Kutilin
 
Vol 22, No 3 (2023) Schisandrin and Schisantherin A in Multiphytoadaptogen for Preventive Oncology Abstract   PDF (Rus)
O. A. Bocharova, I. V. Kazeev, V. E. Shevchenko, N. S. Ionov, O. P. Sheichenko, E. V. Bocharov, R. V. Karpova, V. G. Kucheryanu, A. A. Lagunin, D. A. Filimonov, V. S. Kosorukov, V. V. Poroikov, V. A. Tutelyan, N. V. Pyatigorskaya
 
Vol 22, No 3 (2023) Study of biocompatibility and antitumor cytotoxic activity in vitro of Zn – 1 %Mg and Zn – 1 %Mg – 0.1 %Ca alloys strengthened by equal angular pressing Abstract   PDF (Rus)
N. S. Martynenko, N. Yu. Anisimova, O. V. Rybalchenko, M. V. Shinkareva, D. R. Temralieva, K. M. Novruzov, A. G. Raab, E. A. Lukyanova, E. A. Kornyushenkov, D. V. Filonenko, D. E. Mitrushkin, S. V. Dobatkin
 
Vol 22, No 3 (2023) Combined photodynamic and radiodynamic therapy with a chlorine photosensitizer under fractionated radiation exposure to transplanted tumors in an in vivo experiment Abstract   PDF (Rus)
D. A. Tzerkovsky, A. N. Mazurenko, D. I. Kozlovsky, N. D. Adamenko, F. F. Borichevsky
 
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